SCHEMBL31305652

SCHEMBL31305652

O=C1[C@H](Cc2ccc(O)c(O)c2)NC(=S)N1c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.75
CYP1A2 P05177 1/20 0.71
CYP3A4 P08684 1/20 0.71
CYP2C19 P33261 1/20 0.71
MAPT P10636 3/20 0.65
KDM4E B2RXH2 1/20 0.65
ALDH1A1 P00352 1/20 0.60
RAB9A P51151 2/20 0.54
NPC1 O15118 1/20 0.54
ATM Q13315 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
UBE2N P61088 1/20 0.54
POLB P06746 1/20 0.47
IDH1 O75874 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NR1H3 Q13133 2/20 0.43
TAS2R8 Q9NYW2 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NR1H2 P55055 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8291275 0.86 GAA (1.00) GAACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL110364 0.84 GAA (1.00) GAACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL8290538 0.79 MAPT (1.00) GAACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL8291507 0.77 GAA (0.62) GAACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL12877356 0.74 GAA (0.70) GAACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL13879573 0.73 GAA (0.78) GAACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL13898831 0.72 GAA (0.74) GAACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL8289554 0.72 GAA (0.75) GAACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL8291488 0.72 GAA (0.67) GAACYP1A2CYP3A4CYP2C19MAPT
SCHEMBL109040 0.71 GAA (0.50) GAAMAPTKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119176768-A Preparation method and application of catechol derivatives and administration and preparation device 海南大学 2024-12-24 CN disclosed