Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861277 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL25399112 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL7132652 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL14514898 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL2865352 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL387622 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL15140950 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL3933949 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL18475405 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL11990212 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007074-A1 | CHEMICAL COMPOUNDS | REACTIVE BIOSCIENCES, INC. (US) | 2025-01-02 | — | — | WO | disclosed |