Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.40 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31306487 | 0.93 | CRBN (0.49) | CRBNDDB1IKZF3HTR7MAPT | |
| SCHEMBL31306467 | 0.91 | CRBN (0.50) | CRBNDDB1IKZF3HTR7MAPT | |
| SCHEMBL31306495 | 0.90 | CRBN (0.50) | CRBNDDB1IKZF3HTR7MAPT | |
| SCHEMBL31306513 | 0.88 | CRBN (0.50) | CRBNDDB1IKZF3HTR7MAPT | |
| SCHEMBL31306519 | 0.86 | CRBN (0.51) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL31306511 | 0.84 | CRBN (0.51) | CRBNDDB1HTR7AREGFR | |
| SCHEMBL31306493 | 0.84 | CRBN (0.54) | CRBNDDB1IKZF3HTR7MAPT | |
| SCHEMBL31306531 | 0.84 | CRBN (0.52) | CRBNDDB1HTR7AREGFR | |
| SCHEMBL31306527 | 0.83 | CRBN (0.53) | CRBNDDB1IKZF3HTR7MAPT | |
| SCHEMBL31306505 | 0.83 | CRBN (0.53) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019370-A | Degradation agent targeting SIRT6 and/or GSPT1 and application thereof | 深圳大学 | 2024-11-26 | — | — | CN | disclosed |