Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | IL1B | P01584 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31306524 | 0.95 | CRBN (0.50) | CRBNDDB1EGFR | |
| SCHEMBL31306472 | 0.92 | CRBN (0.52) | CRBNDDB1LMNAIKZF3TNF | |
| SCHEMBL31306468 | 0.88 | CRBN (0.48) | CRBNDDB1IKZF3HTR7 | |
| SCHEMBL31306538 | 0.87 | CRBN (0.58) | CRBNDDB1LMNAIKZF3TNF | |
| SCHEMBL31306515 | 0.86 | CRBN (0.57) | CRBNDDB1LMNAIKZF3TNF | |
| SCHEMBL31306501 | 0.85 | CRBN (0.56) | CRBNDDB1LMNAIKZF3TNF | |
| SCHEMBL31306479 | 0.85 | CRBN (0.55) | CRBNDDB1LMNAIKZF3TNF | |
| SCHEMBL31306506 | 0.85 | CRBN (0.55) | CRBNDDB1EGFR | |
| SCHEMBL31306508 | 0.84 | CRBN (0.54) | CRBNDDB1LMNAIKZF3TNF | |
| SCHEMBL31306480 | 0.83 | CRBN (0.53) | CRBNDDB1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019370-A | Degradation agent targeting SIRT6 and/or GSPT1 and application thereof | 深圳大学 | 2024-11-26 | — | — | CN | disclosed |