⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14787452 | 0.76 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL14786972 | 0.74 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL14787510 | 0.74 | — | — | |
| SCHEMBL12183132 | 0.74 | — | — | |
| SCHEMBL14791353 | 0.71 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL14781274 | 0.71 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL12182864 | 0.69 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL12182854 | 0.69 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL14791351 | 0.69 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL13424256 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119278043-A | Nucleoside LINE-1 inhibitors | 转位治疗股份有限公司 | 2025-01-07 | — | — | CN | disclosed |