Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22094548 | 1.00 | TP53 (0.40) | TP53LMNAMAPTPOLBCYP19A1 | |
| SCHEMBL31308986 | 0.79 | MAPT (0.40) | TP53LMNAMAPTPOLBALDH1A1 | |
| SCHEMBL22095224 | 0.79 | MAPT (0.40) | TP53LMNAMAPTPOLBALDH1A1 | |
| SCHEMBL22094055 | 0.77 | SMN1; SMN2 (0.40) | TP53LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31309104 | 0.77 | SMN1; SMN2 (0.40) | TP53LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25198255 | 0.76 | CYP19A1 (0.36) | CYP19A1NOTUM | |
| SCHEMBL22095076 | 0.69 | NOTUM (0.39) | CYP19A1NOTUM | |
| SCHEMBL31309043 | 0.69 | NOTUM (0.39) | CYP19A1NOTUM | |
| SCHEMBL25003928 | 0.69 | NOTUM (0.40) | CYP19A1NOTUM | |
| SCHEMBL22094765 | 0.66 | NOTUM (0.37) | LMNAMAPTCYP19A1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113923988-B | Substituted arylmethyl ureas and heteroarylmethyl ureas, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2024-12-13 | — | — | CN | disclosed |