Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130918 | 1.00 | F10 (0.65) | F10PTGS2MTOR | |
| SCHEMBL3126191 | 0.90 | F10 (0.79) | F10PTGS2MTOR | |
| SCHEMBL3137853 | 0.90 | F10 (0.65) | F10PTGS2MTOR | |
| SCHEMBL3126166 | 0.90 | F10 (0.79) | F10PTGS2MTOR | |
| SCHEMBL3132838 | 0.90 | F10 (0.65) | F10PTGS2MTOR | |
| SCHEMBL3132856 | 0.90 | F10 (0.65) | F10PTGS2MTOR | |
| SCHEMBL3137875 | 0.90 | F10 (0.65) | F10PTGS2MTOR | |
| SCHEMBL3138466 | 0.87 | F10 (0.64) | F10 | |
| SCHEMBL3138445 | 0.87 | F10 (0.64) | F10 | |
| SCHEMBL14078400 | 0.86 | F10 (0.60) | F10PTGS2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597244-B1 | ETHYNYL DERIVATIVES SERVING AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2010-07-07 | — | — | EP | claimed |
| US-7427618-B2 | Ethynyl derivatives as factor Xa inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-23 | — | — | US | claimed |