Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833545 | 0.89 | CHRM2 (0.41) | KMT2AALDH1A1KDM4ECHRM2CHRM4 | |
| SCHEMBL18387515 | 0.89 | CHRM2 (0.41) | KMT2AALDH1A1KDM4ECHRM2CHRM4 | |
| SCHEMBL9220238 | 0.89 | CHRM2 (0.41) | KMT2AALDH1A1KDM4ECHRM2CHRM4 | |
| SCHEMBL19408441 | 0.89 | CHRM2 (0.41) | KMT2AALDH1A1KDM4ECHRM2CHRM4 | |
| SCHEMBL1444237 | 0.89 | CHRM2 (0.41) | KMT2AALDH1A1KDM4ECHRM2CHRM4 | |
| SCHEMBL19465331 | 0.88 | CHRM2 (0.43) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL28593949 | 0.88 | CHRM2 (0.43) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL1439745 | 0.88 | CHRM2 (0.43) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL29940175 | 0.84 | CHRM2 (0.41) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL16023506 | 0.80 | MAPT (0.52) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735433-A2 | SUBSTITUTED PYRIDAZINE COMPOUNDS AS INHIBITORS OF NLRP3 ACTIVITY AND THERAPEUTIC USES THEREOF | Viva Star Biosciences (US) Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006681-A2 | SUBSTITUTED PYRIDAZINE COMPOUNDS AS INHIBITORS OF NLRP3 ACTIVITY AND THERAPEUTIC USES THEREOF | VIVA STAR BIOSCIENCES (US) INC. (US) | 2025-01-02 | — | — | WO | disclosed |