Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PAK4 | O96013 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.30 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12077911 | 0.80 | PDE10A (0.43) | AHRPDE10AKDM4EALDH1A1 | |
| SCHEMBL20605163 | 0.74 | KDM4E (0.41) | AHRCYP11B2PDE10AKDM4EALDH1A1 | |
| SCHEMBL15539271 | 0.74 | AHR (0.41) | AHRPDE10AKDM4EALDH1A1MAPK1 | |
| SCHEMBL31456654 | 0.74 | AHR (0.41) | AHR | |
| SCHEMBL31264174 | 0.72 | AURKA (0.43) | AHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL31310205 | 0.71 | AHR (0.36) | AHRNR4A2 | |
| SCHEMBL20986019 | 0.71 | AHR (0.50) | AHR | |
| SCHEMBL30842034 | 0.70 | CYP11B1 (0.46) | AHRCYP11B2PIK3CDPIK3CAPIK3CG | |
| SCHEMBL9105398 | 0.70 | AHR (0.41) | AHRCYP11B2KDM4EALDH1A1PIK3CD | |
| SCHEMBL31456625 | 0.70 | AHR (0.38) | AHRCYP11B2KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264042-A | Cyclopentane derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-01-07 | — | — | CN | disclosed |