Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.49 |
| ▸ | PRAP1 | Q96NZ9 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31312131 | 0.98 | PARP1 (0.47) | PARP1PRAP1HDAC1HDAC6PARP2 | |
| SCHEMBL31312469 | 0.95 | PARP1 (0.51) | PARP1PRAP1HDAC1HDAC6PARP2 | |
| SCHEMBL31311770 | 0.93 | PARP1 (0.49) | PARP1PRAP1HDAC1HDAC6PARP2 | |
| SCHEMBL31311558 | 0.93 | PARP1 (0.50) | PARP1PRAP1HDAC1HDAC6PARP2 | |
| SCHEMBL31312280 | 0.92 | PARP1 (0.49) | PARP1PRAP1PARP2 | |
| SCHEMBL31311918 | 0.91 | PARP1 (0.48) | PARP1PRAP1 | |
| SCHEMBL31311726 | 0.90 | PARP1 (0.52) | PARP1PRAP1HDAC1HDAC6PARP2 | |
| SCHEMBL31312022 | 0.89 | PARP1 (0.47) | PARP1PRAP1PARP2 | |
| SCHEMBL31311395 | 0.89 | PARP1 (0.50) | PARP1PRAP1HDAC1HDAC6PARP2 | |
| SCHEMBL31312023 | 0.88 | PARP1 (0.51) | PARP1PRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024264072-A2 | PARP INHIBITORS | Stablix, Inc. (US) | 2024-12-26 | — | — | WO | disclosed |