Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIK1 | P57059 | 4/20 | 0.38 |
| ▸ | SIK2 | Q9H0K1 | 4/20 | 0.38 |
| ▸ | SIK3 | Q9Y2K2 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | CSF1R | P07333 | 3/20 | 0.38 |
| ▸ | LYN | P07948 | 3/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 7/20 | 0.37 |
| ▸ | FLT3 | P36888 | 5/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.37 |
| ▸ | RET | P07949 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31313218 | 0.95 | SYK (0.42) | SIK1SIK2SIK3ABL1CSF1R | |
| SCHEMBL31313095 | 0.94 | SIK1 (0.38) | SIK1SIK2SIK3ABL1CSF1R | |
| SCHEMBL31313368 | 0.92 | SIK1 (0.46) | SIK1SIK2SIK3ABL1CSF1R | |
| SCHEMBL31313128 | 0.91 | SYK (0.42) | SIK1SIK2SIK3ABL1CSF1R | |
| SCHEMBL31313343 | 0.90 | SIK1 (0.39) | SIK1SIK2SIK3ABL1CSF1R | |
| SCHEMBL31313208 | 0.89 | SIK1 (0.42) | SIK1SIK2SIK3ABL1CSF1R | |
| SCHEMBL31313311 | 0.88 | SIK1 (0.37) | SIK1SIK2SIK3ABL1CSF1R | |
| SCHEMBL31313340 | 0.88 | SYK (0.43) | SIK1SIK2SIK3ABL1CSF1R | |
| SCHEMBL31313341 | 0.88 | SYK (0.41) | SIK1SIK2SIK3ABL1CSF1R | |
| SCHEMBL31313366 | 0.86 | SIK1 (0.35) | SIK1SIK2SIK3ABL1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737443-A1 | SALT-INDUCIBLE KINASE INHIBITORY COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Tanabe Pharma Corporation (JP) | 2026-05-06 | — | — | EP | disclosed |
| US-20260062387-A1 | SALT-INDUCIBLE KINASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2026-03-05 | — | — | US | disclosed |
| WO-2024242169-A1 | SALT-INDUCIBLE KINASE INHIBITORY COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 田辺三菱製薬株式会社 | 2024-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062387-A1 | SALT-INDUCIBLE KINASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | SIK1, SIK3, SIK2 | SIK1 1/4885SIK2 3/4885SIK3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.