Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24009682 | 0.84 | CNR2 (0.57) | CNR2DRD4MOGAT2DRD2DRD3 | |
| SCHEMBL24009674 | 0.84 | CNR2 (0.57) | CNR2DRD4MOGAT2DRD2DRD3 | |
| SCHEMBL24002139 | 0.84 | CNR2 (0.57) | CNR2DRD4MOGAT2DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL29069504 | 0.83 | CNR2 (0.56) | CNR2DRD4MOGAT2DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL27166804 | 0.83 | CNR2 (0.56) | CNR2DRD4MOGAT2DRD2DRD3 | |
| SCHEMBL26988794 | 0.81 | CNR2 (0.56) | CNR2DRD4MOGAT2 | |
| SCHEMBL24836219 | 0.77 | CNR2 (0.53) | CNR2MOGAT2 | |
| SCHEMBL31138777 | 0.76 | CNR2 (0.53) | CNR2DRD4MOGAT2 | |
| SCHEMBL31330587 | 0.74 | CNR2 (0.51) | CNR2DRD4MOGAT2 | |
| SCHEMBL31313889 | 0.74 | CNR2 (0.51) | CNR2DRD4MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727934-A1 | TREM2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024260929-A1 | TREM2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-26 | — | — | WO | disclosed |