Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | FUBP1 | Q96AE4 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15175758 | 1.00 | TP53 (0.53) | TP53MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL18337079 | 0.77 | KDM4E (0.47) | TP53MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL15176266 | 0.75 | FYN (0.45) | TP53MAPTFUBP1TDP1PIK3CG | |
| SCHEMBL3513641 | 0.73 | FYN (0.74) | FYN | |
| SCHEMBL12953045 | 0.73 | PIK3CG (0.67) | TP53MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL15176064 | 0.72 | MAPT (0.50) | TP53MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL30602254 | 0.72 | SMN1; SMN2 (0.54) | TP53MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL15176054 | 0.72 | SMN1; SMN2 (0.54) | TP53MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL15174228 | 0.72 | FYN (0.41) | TP53MAPTTSHRFUBP1TDP1 | |
| SCHEMBL10690765 | 0.72 | KDM4E (0.61) | TP53MAPTRAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528903-A | Compounds for the treatment of spinal muscular atrophy | PTC医疗公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-108299314-B | Compounds for the treatment of spinal muscular atrophy | PTC医疗公司 | 2024-11-26 | — | — | CN | disclosed |