Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.64 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | AKT2 | P31751 | 1/20 | 0.51 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24913140 | 1.00 | PIK3CA (0.64) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL24912662 | 1.00 | PIK3CA (0.64) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL30216406 | 1.00 | PIK3CA (0.64) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL26997638 | 0.95 | PIK3CA (0.63) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL24912671 | 0.94 | PIK3CA (0.66) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL30216343 | 0.94 | PIK3CA (0.66) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL24912736 | 0.94 | PIK3CA (0.66) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL31316442 | 0.92 | PIK3CA (0.56) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL26662743 | 0.92 | PIK3CA (0.56) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL26662739 | 0.92 | PIK3CA (0.56) | PIK3CAAKT1AKT2AKT3PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301106-A | Allosteric benzopyrone inhibitors of phosphoinositide 3-kinase (PI 3K) for the treatment of disease | 佩特拉制药公司 | 2025-01-10 | — | — | CN | disclosed |