Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PTGFR | P43088 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
| ▸ | PTGIR | P43119 | 1/20 | 0.50 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517861 | 1.00 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL8517862 | 1.00 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL31318330 | 1.00 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL1051005 | 0.91 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL1046738 | 0.91 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL1046739 | 0.91 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL1051004 | 0.91 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL14584000 | 0.89 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL12787968 | 0.87 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL12787980 | 0.86 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306665-A | 3- (1- (2, 4-Dichlorobenzyl) -1H-indazol-3-yl) benzoyl hydrazine, and preparation method and application thereof | 浙江大学医学院附属邵逸夫医院（浙江省邵逸夫医院） | 2025-01-14 | — | — | CN | disclosed |