Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.57 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31319814 | 0.89 | KDR (0.48) | KDRRETPDGFRBFGFR1PDGFRA | |
| SCHEMBL17034026 | 0.84 | KDR (0.65) | KDRRETPDGFRBFGFR1PDGFRA | |
| SCHEMBL29550321 | 0.84 | KDR (0.65) | KDRRETPDGFRBFGFR1PDGFRA | |
| SCHEMBL31319775 | 0.82 | KDR (0.63) | KDR | |
| SCHEMBL31319765 | 0.82 | KDR (0.57) | KDRRETPDGFRBFGFR1PDGFRA | |
| SCHEMBL31319837 | 0.79 | KDR (0.49) | KDRRETPDGFRBFGFR1PDGFRA | |
| SCHEMBL31319810 | 0.78 | KDR (0.65) | KDRRETPDGFRBFGFR1PDGFRA | |
| SCHEMBL31319789 | 0.76 | KDR (0.68) | KDR | |
| SCHEMBL421224 | 0.76 | KDR (0.41) | KDRFLT1 | |
| SCHEMBL17034040 | 0.75 | KDR (0.67) | KDRRETPDGFRBFGFR1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219561-A | Naphthamide 1H-indazole derivative and preparation and application thereof | 上海润石医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |