Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.84 |
| ▸ | EGFR | P00533 | 15/20 | 0.84 |
| ▸ | FGFR1 | P11362 | 13/20 | 0.84 |
| ▸ | FLT1 | P17948 | 13/20 | 0.84 |
| ▸ | FLT4 | P35916 | 13/20 | 0.84 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.79 |
| ▸ | RET | P07949 | 3/20 | 0.79 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.79 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.79 |
| ▸ | TEK | Q02763 | 2/20 | 0.79 |
| ▸ | KIF5B | P33176 | 2/20 | 0.79 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.79 |
| ▸ | PLK4 | O00444 | 1/20 | 0.79 |
| ▸ | CIT | O14578 | 1/20 | 0.79 |
| ▸ | GAK | O14976 | 1/20 | 0.79 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.79 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.79 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.79 |
| ▸ | STK10 | O94804 | 1/20 | 0.79 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1612820 | 1.00 | KDR (0.84) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL1782681 | 0.94 | KDR (0.75) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL5424040 | 0.91 | KDR (1.00) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL2136908 | 0.91 | EGFR (1.00) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL2140901 | 0.90 | FLT1 (0.98) | KDREGFRFGFR1FLT1FLT4 | |
| Hydrochloric Acid SCHEMBL27218181 | 0.90 | FLT1 (1.00) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL17520370 | 0.89 | KDR (0.79) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL2138023 | 0.89 | KDR (1.00) | KDREGFRFGFR1FLT1FLT4 | |
| Vandetanib SCHEMBL29352879 | 0.89 | EGFR (1.00) | KDREGFRFGFR1FLT1FLT4 | |
| Vandetanib SCHEMBL9044 | 0.89 | EGFR (1.00) | KDREGFRFGFR1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219607-A | Near infrared fluorescent probe for actively targeting vascular epidermal growth factor receptor detection and preparation method and application thereof | 南京诺源医疗器械有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-119219607-B | Near infrared fluorescent probe for actively targeting vascular epidermal growth factor receptor detection and preparation method and application thereof | 南京诺源医疗器械有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119219607-A | Near infrared fluorescent probe for actively targeting vascular epidermal growth factor receptor detection and preparation method and application thereof | 南京诺源医疗器械有限公司 | 2024-12-31 | — | — | CN | disclosed |