Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23062938 | 1.00 | F10 (0.47) | F10KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29448761 | 0.82 | PARP1 (0.61) | F10KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8810191 | 0.82 | F10 (0.64) | F10 | |
| SCHEMBL711132 | 0.82 | PARP1 (0.61) | F10KAT6ATAS1R3TAS1R1TAS1R2 | |
| Hydrochloric Acid SCHEMBL1268771 | 0.81 | PARP1 (0.59) | F10KAT6ATAS1R3TAS1R1TAS1R2 | |
| Hydrochloric Acid SCHEMBL1085083 | 0.81 | F10 (0.62) | F10 | |
| SCHEMBL1580873 | 0.79 | KAT6A (0.46) | F10KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1580875 | 0.79 | KAT6A (0.46) | F10KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29478758 | 0.79 | KAT6A (0.46) | F10KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL12322885 | 0.78 | KAT6A (0.45) | F10KAT6ATAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112119076-B | Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors | 默沙东有限责任公司 | 2025-01-10 | — | — | CN | disclosed |