SCHEMBL31323367

SCHEMBL31323367

COc1ccc(-c2sc(NC(=O)CC3CCCCC3)nc2C)cc1S(=O)(=O)Nc1cccc(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PI4KB Q9UBF8 16/20 1.00
PIK3C2G O75747 5/20 0.75
PIK3CA P42336 2/20 0.68
PIK3CG P48736 2/20 0.68
PIK3CD O00329 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14851588 1.00 PI4KB (1.00) PI4KBPIK3C2GPIK3CAPIK3CGPIK3CD
SCHEMBL31323379 0.99 PI4KB (1.00) PI4KBPIK3C2GPIK3CAPIK3CGPIK3CD
SCHEMBL14851594 0.99 PI4KB (1.00) PI4KBPIK3C2GPIK3CAPIK3CGPIK3CD
SCHEMBL17889529 0.93 PI4KB (0.88) PI4KBPIK3C2GPIK3CAPIK3CGPIK3CD
SCHEMBL16492691 0.92 PI4KB (0.86) PI4KBPIK3C2GPIK3CAPIK3CGPIK3CD
SCHEMBL14851842 0.92 PIK3C2G (0.86) PI4KBPIK3C2GPIK3CAPIK3CGPIK3CD
SCHEMBL31323357 0.91 PI4KB (0.84) PI4KBPIK3C2GPIK3CAPIK3CGPIK3CD
SCHEMBL17889656 0.91 PI4KB (0.84) PI4KBPIK3C2GPIK3CAPIK3CGPIK3CD
SCHEMBL14851577 0.91 PIK3C2G (0.87) PI4KBPIK3C2GPIK3CAPIK3CGPIK3CD
SCHEMBL31323377 0.91 PIK3C2G (0.87) PI4KBPIK3C2GPIK3CAPIK3CGPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3419980-B1 PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY UNIV LELAND STANFORD JUNIOR (US) 2025-01-01 EP disclosed