Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196010 | 1.00 | IDO1 (0.54) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6582712 | 0.83 | CYP3A4 (0.43) | IDO1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL14656662 | 0.82 | HTT (0.65) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29875226 | 0.78 | SLC6A4 (0.56) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30480073 | 0.78 | IDO1 (0.54) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28141985 | 0.78 | IDO1 (0.54) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18500548 | 0.78 | IDO1 (0.54) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2569349 | 0.78 | SLC6A4 (0.56) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8223381 | 0.78 | IDO1 (0.54) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16467121 | 0.78 | KMT2A (0.62) | IDO1MAPK1CYP1A2CYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285617-A | 1,3, 5-Trisubstituted indole derivatives and use thereof | 沈阳药科大学 | 2025-01-10 | — | — | CN | disclosed |