SCHEMBL31324092

SCHEMBL31324092

NC(=O)C1CCCN1C(=O)CNC(=O)CCCCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PREP P48147 1/20 0.59
DPP4 P27487 5/20 0.57
ACE P12821 1/20 0.51
FKBP1A P62942 3/20 0.49
DPP8 Q6V1X1 1/20 0.49
DPP7 Q9UHL4 1/20 0.49
EPHX1 P07099 1/20 0.49
HTR1A P08908 1/20 0.48
HTR7 P34969 1/20 0.48
F2 P00734 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31324104 0.99 PREP (0.58) PREPDPP4ACEFKBP1ADPP8
SCHEMBL26616511 0.97 PREP (0.60) PREPDPP4ACEFKBP1ADPP8
SCHEMBL26616519 0.97 PREP (0.60) PREPDPP4ACEFKBP1ADPP8
SCHEMBL31324102 0.85 DPP4 (0.55) PREPDPP4HTR1AHTR7
SCHEMBL449093 0.84 DPP4 (0.58) DPP4ACEHTR1AHTR7F2
SCHEMBL30530847 0.83 DPP4 (0.56) PREPDPP4ACE
SCHEMBL26616578 0.81 ACE (0.56) ACE
SCHEMBL26616582 0.81 ACE (0.56) ACE
SCHEMBL30182974 0.80 DPP4 (0.48) DPP4ACE
SCHEMBL30182795 0.79 DPP4 (0.47) DPP4ACEHTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795249-B Pharmaceutical compounds for treating complement-mediated disorders 艾其林医药公司 2025-02-25 CN disclosed