Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31691038 | 1.00 | MAPK1 (0.39) | MAPK1IAPPALDH1A1HSD17B10CFTR | |
| SCHEMBL4651223 | 0.90 | MAPK1 (0.43) | MAPK1IAPPALDH1A1HSD17B10CFTR | |
| SCHEMBL31512136 | 0.90 | MAPK1 (0.43) | MAPK1IAPPALDH1A1HSD17B10CFTR | |
| SCHEMBL31691447 | 0.83 | IAPP (0.41) | MAPK1IAPPKDM4EMAPTGAA | |
| SCHEMBL4653578 | 0.79 | IAPP (0.56) | MAPK1IAPPALDH1A1HSD17B10KDM4E | |
| SCHEMBL31326408 | 0.79 | SCN9A (0.39) | MAPK1 | |
| SCHEMBL4652261 | 0.79 | IAPP (0.56) | MAPK1IAPPALDH1A1HSD17B10KDM4E | |
| SCHEMBL4652413 | 0.78 | BCL2 (0.44) | MAPK1IAPPALDH1A1HSD17B10CFTR | |
| SCHEMBL31691414 | 0.78 | IAPP (0.38) | MAPK1IAPPMAPTGAASMN1; SMN2 | |
| SCHEMBL31528959 | 0.77 | MAPK8 (0.36) | IAPPALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350323-B | N-sulfonyl amide nitrogen-containing fused heterocycle compounds targeting p53 mutation and application thereof | 上海宇道生物技术有限公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025077778-A1 | CARBOXYLIC ACID COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海宇道生物技术有限公司 | 2025-04-17 | — | — | WO | disclosed |
| WO-2025077783-A1 | DEUTERATED INDOLIZINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海宇道生物技术有限公司 | 2025-04-17 | — | — | WO | disclosed |
| CN-119350323-A | N-sulfonyl amide nitrogen-containing fused heterocycle compounds targeting p53 mutation and application thereof | 上海宇道生物技术有限公司 | 2025-01-24 | — | — | CN | disclosed |
| WO-2025011684-A2 | N-SULFONAMIDE NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUND, AND APPLICATION THEREOF | 上海宇道生物技术有限公司 | 2025-01-16 | — | — | WO | disclosed |