Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21978634 | 1.00 | PTPRA (0.51) | PTPRACYP1A2FDPSSMN1; SMN2TSHR | |
| SCHEMBL21978636 | 1.00 | PTPRA (0.51) | PTPRACYP1A2FDPSSMN1; SMN2TSHR | |
| SCHEMBL21978581 | 0.87 | HDAC6 (0.46) | PTPRACYP1A2FDPSSMN1; SMN2TSHR | |
| SCHEMBL21978531 | 0.87 | HDAC6 (0.46) | PTPRACYP1A2FDPSSMN1; SMN2TSHR | |
| SCHEMBL27954184 | 0.85 | PTPRA (0.47) | PTPRACYP1A2FDPSSMN1; SMN2TSHR | |
| SCHEMBL30191609 | 0.81 | KMT2A (0.41) | SMN1; SMN2CA2CA9CPA1CPB1 | |
| SCHEMBL22035812 | 0.81 | KMT2A (0.41) | SMN1; SMN2CA2CA9CPA1CPB1 | |
| SCHEMBL1704171 | 0.80 | CPA1 (0.60) | CYP1A2CA2CA9CPA1CPB1 | |
| SCHEMBL1704913 | 0.80 | CPA1 (0.60) | CYP1A2CA2CA9CPA1CPB1 | |
| SCHEMBL1915766 | 0.80 | CPA1 (0.60) | CYP1A2CA2CA9CPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166114-B | Cyclic tetramer compounds as inhibitors of proprotein convertase subtilisin/KEXIN type 9 (PCSK 9) for the treatment of metabolic disorders | 诺华股份有限公司 | 2025-01-03 | — | — | CN | disclosed |