Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128039 | 0.88 | PIK3CA (0.81) | PIK3CAMTOR | |
| SCHEMBL3119568 | 0.87 | PIK3CA (0.79) | PIK3CAMTOR | |
| SCHEMBL3133386 | 0.86 | PIK3CA (0.83) | PIK3CAMTOR | |
| SCHEMBL3480028 | 0.85 | PIK3CA (0.85) | PIK3CAMTOR | |
| SCHEMBL3128114 | 0.85 | PIK3CA (0.85) | PIK3CAMTOR | |
| SCHEMBL3130047 | 0.85 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL3132760 | 0.84 | PIK3CA (0.80) | PIK3CAMTOR | |
| SCHEMBL3128416 | 0.83 | PIK3CA (0.85) | PIK3CAMTOR | |
| SCHEMBL4990174 | 0.82 | MTOR (0.77) | PIK3CAMTOR | |
| SCHEMBL3132298 | 0.81 | MTOR (0.78) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002954-A1 | (2-ARYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)MORPHOLINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH (US) | 2010-01-07 | — | — | WO | claimed |