Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18156543 | 0.84 | CYP3A4 (0.36) | SLC6A4CYP3A4HTTSMN1; SMN2ABL1 | |
| Hydrochloric Acid SCHEMBL16616945 | 0.84 | CYP3A4 (0.36) | SLC6A4CYP3A4HTTSMN1; SMN2ABL1 | |
| SCHEMBL31328726 | 0.78 | CYP3A4 (0.31) | CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL31328725 | 0.78 | CYP3A4 (0.31) | CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL30558133 | 0.76 | ABL1 (0.36) | CYP3A4HTTSMN1; SMN2ABL1ALDH1A1 | |
| SCHEMBL31328572 | 0.76 | — | — | |
| SCHEMBL30558116 | 0.75 | ABL1 (0.36) | SMN1; SMN2ABL1ALDH1A1 | |
| SCHEMBL28491743 | 0.72 | ABL1 (0.38) | CYP3A4HTTSMN1; SMN2ABL1ALDH1A1 | |
| SCHEMBL31252206 | 0.70 | ABL1 (0.39) | SIGMAR1CYP3A4HTTSMN1; SMN2ABL1 | |
| SCHEMBL31328570 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025040767-A1 | 2-(3,8-DIAZABICYCLO[3.2.1]OCTAN-3-YL)-1,3,5-TRIAZINE DERIVATIVES AS KRAS G12D INHIBITORS FOR THE TREATMENT OF CANCER | SANOFI (FR) | 2025-02-27 | — | — | WO | disclosed |