SCHEMBL31329152

SCHEMBL31329152

COc1ccc(F)cc1C(=O)NCc1ccc(-c2nc(C3CCS(=O)(=O)CC3)cc3[nH]nc(N)c23)cc1

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BTK Q06187 10/20 0.58
EGFR P00533 8/20 0.51
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
MAPK1 P28482 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31329079 0.91 BTK (0.59) BTKEGFRLMNATP53MAPK1
SCHEMBL31328892 0.91 BTK (0.59) BTKEGFRLMNATP53MAPK1
SCHEMBL31328820 0.91 BTK (0.59) BTKEGFRLMNATP53MAPK1
SCHEMBL31328975 0.91 BTK (0.59) BTKEGFRLMNATP53MAPK1
SCHEMBL31329006 0.87 BTK (0.58) BTKEGFRLMNATP53MAPK1
Hydrochloric Acid SCHEMBL31328951 0.87 BTK (0.58) BTKEGFRLMNATP53MAPK1
SCHEMBL38652645 0.87 BTK (0.56) BTKEGFRLMNATP53MAPK1
SCHEMBL31329119 0.85 BTK (0.64) BTKEGFRMAPK1
SCHEMBL31329024 0.83 BTK (0.59) BTKEGFRLMNATP53MAPK1
SCHEMBL31328980 0.83 BTK (0.57) BTKEGFRLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741392-A1 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF Shenzhen TargetRx Co., Ltd. (CN) 2026-05-13 EP disclosed
WO-2025007863-A1 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF 深圳市塔吉瑞生物医药有限公司 2025-01-09 WO disclosed