Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.72 |
| ▸ | RAB9A | P51151 | 11/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | PKM | P14618 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | SCD | O00767 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17372932 | 1.00 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL11706323 | 0.90 | NPC1 (0.83) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL11705400 | 0.84 | NPC1 (0.74) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL27724289 | 0.83 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL11706898 | 0.83 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL28376614 | 0.83 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL2243443 | 0.83 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL27877970 | 0.83 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL11708813 | 0.81 | SCD (0.76) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL11706220 | 0.81 | NPC1 (0.74) | NPC1RAB9AMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330886-A | Benzimidazole amine derivative, preparation method thereof and beta2Use of allosteric antagonists of adrenergic receptors | 常州大学 | 2025-01-21 | — | — | CN | disclosed |