Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 16/20 | 0.63 |
| ▸ | CCND1 | P24385 | 11/20 | 0.63 |
| ▸ | CCND3 | P30281 | 6/20 | 0.52 |
| ▸ | CDK4 | P11802 | 5/20 | 0.52 |
| ▸ | CDK1 | P06493 | 5/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619505 | 0.86 | CDK6 (0.72) | CDK6CCND1CCND3CDK4DYRK2 | |
| SCHEMBL28610126 | 0.79 | CDK6 (1.00) | CDK6CCND1CCND3CDK4CDK1 | |
| SCHEMBL29896876 | 0.79 | CDK6 (1.00) | CDK6CCND1CCND3CDK4CDK1 | |
| SCHEMBL28610131 | 0.77 | CDK6 (0.72) | CDK6CCND1CCND3CDK4CDK1 | |
| SCHEMBL24483228 | 0.77 | DYRK2 (0.60) | CDK6CCND1CDK4DYRK2 | |
| SCHEMBL29684290 | 0.77 | DYRK2 (0.60) | CDK6CCND1CDK4DYRK2 | |
| SCHEMBL30569706 | 0.76 | DYRK2 (0.81) | CDK6DYRK2 | |
| SCHEMBL26447886 | 0.76 | DYRK2 (0.81) | CDK6DYRK2 | |
| SCHEMBL18823161 | 0.76 | CDK4 (0.72) | CDK6CCND3CDK4CDK1CCNA2 | |
| SCHEMBL18081366 | 0.75 | CDK6 (0.71) | CDK6CCND1CCND3CDK4CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371410-A | Chromone spiro compound and preparation method and application thereof | 中国药科大学 | 2025-01-28 | — | — | CN | disclosed |