Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376876 | 0.73 | HPGD (0.41) | KDM4EMEN1KMT2ACSNK2A1DYRK1A | |
| SCHEMBL31135882 | 0.68 | CSNK2A1 (0.45) | MEN1KMT2ACSNK2A1DYRK1ACSNK2A2 | |
| SCHEMBL20399971 | 0.68 | CSNK2A1 (0.45) | MEN1KMT2ACSNK2A1DYRK1ACSNK2A2 | |
| SCHEMBL16475165 | 0.68 | CSNK2A1 (0.45) | MEN1KMT2ACSNK2A1DYRK1ACSNK2A2 | |
| SCHEMBL30206320 | 0.67 | MEN1 (0.43) | KDM4EMEN1KMT2ACSNK2A1DYRK1A | |
| SCHEMBL22533554 | 0.67 | KDM4E (0.39) | KDM4EMEN1KMT2ACSNK2A1DYRK1A | |
| SCHEMBL13765863 | 0.67 | MEN1 (0.43) | KDM4EMEN1KMT2ACSNK2A1DYRK1A | |
| SCHEMBL22576013 | 0.67 | AHR (0.38) | CSNK2A1DYRK1AALDH1A1IGF1RDYRK1B | |
| SCHEMBL30026260 | 0.67 | MEN1 (0.43) | KDM4EMEN1KMT2ACSNK2A1DYRK1A | |
| SCHEMBL16094994 | 0.67 | MEN1 (0.43) | KDM4EMEN1KMT2ACSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024249817-A1 | TRICYCLIC PKMYT1 KINASE INHIBITORS | ENLIVEN INC. (US) | 2024-12-05 | — | — | WO | disclosed |