Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31278989 | 0.87 | RXFP1 (0.30) | RXFP1 | |
| SCHEMBL31278641 | 0.81 | EGFR (0.40) | RXFP1KMT2ALMNA | |
| SCHEMBL26988300 | 0.81 | EGFR (0.40) | RXFP1KMT2ALMNA | |
| SCHEMBL31330595 | 0.77 | RXFP1 (0.33) | RXFP1 | |
| SCHEMBL31330832 | 0.77 | KDM4E (0.32) | RXFP1 | |
| SCHEMBL31279024 | 0.76 | CYP1A2 (0.38) | RXFP1 | |
| SCHEMBL31330766 | 0.75 | — | — | |
| SCHEMBL31330633 | 0.75 | PARG (0.38) | — | |
| SCHEMBL25358585 | 0.74 | ADORA2A (0.41) | KMT2ALMNA | |
| SCHEMBL31330622 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720061-A1 | TREM2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246018-A1 | TREM2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-05 | — | — | WO | disclosed |