Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.39 |
| ▸ | WIZ | O95785 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331010 | 0.86 | CRBN (0.53) | CRBNDDB1ARGRAMD1A | |
| SCHEMBL22291497 | 0.83 | CRBN (0.44) | CRBNDDB1GPR119 | |
| SCHEMBL29367335 | 0.83 | CRBN (0.44) | CRBNDDB1GPR119 | |
| SCHEMBL20231478 | 0.81 | CRBN (0.55) | CRBNDDB1GPR119AR | |
| SCHEMBL22291619 | 0.81 | DDB1 (0.55) | CRBNDDB1 | |
| SCHEMBL22291670 | 0.80 | ALK (0.38) | CRBNDDB1GPR119AR | |
| SCHEMBL26147997 | 0.80 | CRBN (0.44) | CRBNDDB1WIZ | |
| SCHEMBL30275734 | 0.80 | CRBN (0.44) | CRBNDDB1WIZ | |
| SCHEMBL30275693 | 0.80 | CRBN (0.56) | CRBNDDB1AR | |
| SCHEMBL26147868 | 0.80 | CRBN (0.56) | CRBNDDB1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011623-A1 | CYANOQUINOLINE-TARGETING PROTEIN DEGRADATION MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海壹迪生物技术有限公司 | 2025-01-16 | — | — | WO | disclosed |