SCHEMBL31331778

SCHEMBL31331778

CN(Cc1ccc(F)cc1)c1ccc2c(C(F)(F)F)cc(=O)[nH]c2c1N

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AR P10275 17/20 0.42
FABP4 P15090 2/20 0.42
DAO P14920 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31331859 0.79 AR (0.45) ARDAO
SCHEMBL31331828 0.70 AR (0.43) ARDAO
SCHEMBL6679452 0.70 AR (0.54) AR
SCHEMBL6676714 0.70 AR (0.50) AR
SCHEMBL31331746 0.69 MEN1 (0.44) ARDAO
SCHEMBL31331858 0.68 GAA (0.49) DAO
SCHEMBL31331908 0.68 AR (0.43) ARDAO
SCHEMBL31331610 0.68 AR (0.40) ARDAO
SCHEMBL31331847 0.66 AR (0.59) AR
SCHEMBL13480899 0.64 AR (0.50) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285594-A 7-Aminobenzopyrone or 7-aminoquinolinone compound and application thereof 浙江大学金华研究院 2025-01-10 CN disclosed