Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 3/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 3/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.41 |
| ▸ | GPR6 | P46095 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331744 | 0.95 | SUV39H2 (0.45) | JAK3BTKKDM1AMETSYK | |
| SCHEMBL31331831 | 0.92 | BTK (0.47) | JAK3BTKRETMAP4K4MET | |
| SCHEMBL31331669 | 0.91 | JAK3 (0.47) | JAK3BTKRETMAP4K4KDM1A | |
| SCHEMBL31331787 | 0.91 | JAK3 (0.48) | JAK3BTKRETMAP4K4MET | |
| SCHEMBL31331894 | 0.90 | JAK3 (0.49) | JAK3BTKRETMAP4K4MET | |
| SCHEMBL31331798 | 0.89 | JAK3 (0.48) | JAK3BTKRETMAP4K4MET | |
| SCHEMBL31331768 | 0.87 | SUV39H2 (0.50) | JAK3BTKKDM1AMETSUV39H2 | |
| SCHEMBL31331845 | 0.86 | SUV39H2 (0.46) | JAK3BTKMETSYKSUV39H2 | |
| SCHEMBL31331874 | 0.86 | SUV39H2 (0.47) | JAK3BTKMETSYKSUV39H2 | |
| SCHEMBL31331898 | 0.85 | SUV39H2 (0.48) | JAK3BTKMAP4K4METSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285613-A | Substituted quinoxaline and quinazolinone compounds and uses thereof | 河南中医药大学 | 2025-01-10 | — | — | CN | disclosed |