SCHEMBL31332200

SCHEMBL31332200

COC(=O)N1CC(c2nc(-c3cc(F)c(C)c(NC(=O)c4cnc5cc(C(N)=O)ccn45)c3)no2)C1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIT P10721 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30601482 1.00 KIT (0.54) KIT
SCHEMBL30601476 0.92 KIT (0.63) KIT
SCHEMBL26626697 0.92 KIT (0.63) KIT
SCHEMBL30601489 0.92 KIT (0.63) KIT
SCHEMBL26626694 0.92 KIT (0.63) KIT
SCHEMBL30601454 0.91 KIT (0.57) KIT
SCHEMBL30601356 0.91 KIT (0.55) KIT
SCHEMBL26626708 0.91 KIT (0.57) KIT
SCHEMBL26851353 0.91 KIT (0.55) KIT
SCHEMBL31332174 0.90 KIT (0.58) KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119384421-A Certain chemical entities, compositions and methods 沐尔佳治疗公司 2025-01-28 CN claimed
CN-119384421-A Certain chemical entities, compositions and methods 沐尔佳治疗公司 2025-01-28 CN disclosed