Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.60 |
| ▸ | CDK2 | P24941 | 20/20 | 0.60 |
| ▸ | GSK3B | P49841 | 14/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559432 | 0.87 | CCNE1 (0.58) | CCNE1CDK2GSK3B | |
| SCHEMBL3564951 | 0.80 | CDK2 (0.47) | CCNE1CDK2GSK3B | |
| SCHEMBL3559853 | 0.75 | CDK2 (0.55) | CCNE1CDK2 | |
| SCHEMBL22311990 | 0.75 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22312476 | 0.75 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22312863 | 0.75 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL25941301 | 0.75 | CDK2 (0.67) | CCNE1CDK2GSK3B | |
| SCHEMBL25938137 | 0.75 | CDK2 (0.67) | CCNE1CDK2GSK3B | |
| SCHEMBL22311156 | 0.75 | CCNE1 (1.00) | CCNE1CDK2GSK3B | |
| SCHEMBL22311982 | 0.75 | CCNE1 (1.00) | CCNE1CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689721-B1 | AMINOPYRAZOLE DERIVATIVES AS GSK-3 INHIBITORS | PFIZER PROD INC (US) | 2010-07-14 | — | — | EP | disclosed |