Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332657 | 1.00 | EPHX2 (0.44) | EPHX2HSD11B1ALDH1A1MAPTPOLB | |
| SCHEMBL31332653 | 0.82 | EPHX2 (0.49) | EPHX2MAPTRAB9ASMN1; SMN2TSHR | |
| SCHEMBL31332801 | 0.82 | EPHX2 (0.49) | EPHX2MAPTRAB9ASMN1; SMN2TSHR | |
| SCHEMBL31332620 | 0.80 | EPHX2 (0.40) | EPHX2ALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL31332799 | 0.79 | POLB (0.53) | EPHX2ALDH1A1MAPTPOLBMAPK1 | |
| SCHEMBL31332790 | 0.78 | TAAR1 (0.37) | ALDH1A1 | |
| SCHEMBL31332634 | 0.77 | EPHX1 (0.54) | EPHX2ALDH1A1MAPTPOLBMAPK1 | |
| SCHEMBL31332705 | 0.77 | EPHX1 (0.54) | EPHX2ALDH1A1MAPTPOLBMAPK1 | |
| SCHEMBL31332607 | 0.76 | EPHX2 (0.46) | EPHX2MAPTRAB9AHPGDTSHR | |
| SCHEMBL31332624 | 0.75 | TAAR1 (0.39) | EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |