Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333463 | 0.93 | RAF1 (0.42) | RAF1BRAFMAPK1CDK2CCNA2 | |
| SCHEMBL31334057 | 0.91 | RAF1 (0.40) | RAF1BRAFMAPK1CDK2CCNA2 | |
| SCHEMBL31333693 | 0.90 | CCNK (0.41) | RAF1BRAFMAPK1CDK2CCNA2 | |
| SCHEMBL31334772 | 0.89 | MAP4K1 (0.40) | BRAFMAPK1CDK2CCNA2MAPK3 | |
| SCHEMBL31333818 | 0.89 | RAF1 (0.43) | RAF1BRAFMAPK1CDK2CCNA2 | |
| SCHEMBL31333975 | 0.88 | PRKD1 (0.40) | MAPK1CDK2CCNA2MAPK3PRKD1 | |
| SCHEMBL31333826 | 0.88 | MAPK1 (0.39) | BRAFMAPK1CDK2CCNA2MAPK3 | |
| SCHEMBL31334003 | 0.88 | MAPK1 (0.49) | RAF1BRAFMAPK1CDK2CCNA2 | |
| SCHEMBL31334480 | 0.87 | MAPK1 (0.45) | RAF1BRAFMAPK1CDK2CCNA2 | |
| SCHEMBL31333902 | 0.87 | MAP4K1 (0.43) | MAPK1CDK2CCNA2MAPK3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |