SCHEMBL31333682

SCHEMBL31333682

O=C1CC[C@H](Nc2ccc(N3CCN([C@H]4CC[C@H](C(=O)N[C@H]5CC[C@H](Nc6ncc(F)c(-c7cccc(-c8ccc[nH]c8=O)c7)n6)CC5)CC4)CC3)c(F)c2)C(=O)N1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 3/20 0.34
CRBN Q96SW2 3/20 0.34
CCNT1 O60563 3/20 0.33
CDK9 P50750 3/20 0.33
CCNK O75909 2/20 0.33
CDK2 P24941 2/20 0.33
CDK12 Q9NYV4 2/20 0.33
MAPK1 P28482 2/20 0.33
CCNA2 P20248 1/20 0.33
CDK7 P50613 1/20 0.33
CCNH P51946 1/20 0.33
CDK13 Q14004 1/20 0.33
SIK1 P57059 2/20 0.33
SIK2 Q9H0K1 2/20 0.33
SIK3 Q9Y2K2 2/20 0.33
SYK P43405 1/20 0.33
CDK4 P11802 4/20 0.33
CSF1R P07333 3/20 0.33
CDK6 Q00534 3/20 0.33
CCND1 P24385 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31335034 1.00 DDB1 (0.34) DDB1CRBNCCNT1CDK9CCNK
SCHEMBL31334035 1.00 DDB1 (0.34) DDB1CRBNCCNT1CDK9CCNK
SCHEMBL31335080 1.00 DDB1 (0.34) DDB1CRBNCCNT1CDK9CCNK
SCHEMBL31333689 1.00 DDB1 (0.34) DDB1CRBNCCNT1CDK9CCNK
SCHEMBL31335054 1.00 DDB1 (0.34) DDB1CRBNCCNT1CDK9CCNK
SCHEMBL31334582 1.00 DDB1 (0.34) DDB1CRBNCCNT1CDK9CCNK
SCHEMBL31334538 0.95 CDK4 (0.35) DDB1CRBNCCNT1CDK9CCNK
SCHEMBL31335022 0.95 CDK4 (0.35) DDB1CRBNCCNT1CDK9CCNK
SCHEMBL31334808 0.95 CDK4 (0.35) DDB1CRBNCCNT1CDK9CCNK
SCHEMBL31335019 0.92 MEN1 (0.39) DDB1CRBNCCNT1CDK9CCNK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed