Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 18/20 | 0.64 |
| ▸ | CDK1 | P06493 | 7/20 | 0.64 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.64 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.64 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 2/20 | 0.50 |
| ▸ | CCND1 | P24385 | 2/20 | 0.50 |
| ▸ | CCND3 | P30281 | 2/20 | 0.50 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334866 | 0.87 | CDK2 (0.60) | CDK2CDK1CCNB1CCNE1CDK5 | |
| SCHEMBL31334016 | 0.87 | CDK2 (0.60) | CDK2CDK1CCNB1CCNE1CDK5 | |
| SCHEMBL31334670 | 0.83 | CDK2 (0.58) | CDK2CDK1CCNB1CCNE1CDK5 | |
| SCHEMBL31334137 | 0.83 | CDK2 (0.58) | CDK2CDK1CCNB1CCNE1CDK5 | |
| SCHEMBL31333442 | 0.82 | CDK2 (0.57) | CDK2CDK1CCNB1CCNE1CDK5 | |
| SCHEMBL31333335 | 0.81 | CDK2 (0.56) | CDK2CDK1CCNB1CCNE1CDK5 | |
| SCHEMBL31334351 | 0.79 | CDK2 (0.58) | CDK2CDK1CCNB1CCNE1CDK5 | |
| SCHEMBL31333541 | 0.79 | CDK2 (0.58) | CDK2CDK1CCNB1CCNE1CDK5 | |
| SCHEMBL31333215 | 0.79 | MAPK1 (0.59) | CDK2MAPK1MAPK3JUNMAPK8 | |
| SCHEMBL22900873 | 0.78 | CCNE1 (1.00) | CDK2CDK1CCNB1CCNE1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |