SCHEMBL31333728

SCHEMBL31333728

CCOC(=O)C(C)Oc1ccc(SCc2nnc(-c3ccc(F)cc3)s2)cc1C

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 13/20 0.43
PPARA Q07869 9/20 0.43
QPCT Q16769 1/20 0.39
QPCTL Q9NXS2 1/20 0.39
PPARG P37231 4/20 0.39
TRPM8 Q7Z2W7 1/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPC1 O15118 1/20 0.37
RORA P35398 1/20 0.37
NR5A1 Q13285 1/20 0.37
MEN1 O00255 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25396403 0.93 KDM4E (0.43) PPARDPPARAQPCTQPCTLPPARG
SCHEMBL31333933 0.91 PPARD (0.41) PPARDPPARAQPCTQPCTLPPARG
SCHEMBL25397724 0.91 PPARD (0.48) PPARDPPARAQPCTQPCTLPPARG
SCHEMBL31333786 0.89 PPARD (0.49) PPARDPPARAPPARGNR5A1
SCHEMBL31333868 0.89 PPARD (0.39) PPARDPPARAQPCTQPCTLPPARG
SCHEMBL30579913 0.87 PPARD (0.53) PPARDPPARAQPCTQPCTLPPARG
SCHEMBL25397774 0.87 PPARD (0.53) PPARDPPARAQPCTQPCTLPPARG
SCHEMBL25397703 0.84 QPCTL (0.41) PPARDPPARAQPCTQPCTLPPARG
SCHEMBL25397032 0.83 PPARD (0.47) PPARDPPARAQPCTQPCTLPPARG
SCHEMBL31408955 0.83 PPARD (0.47) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197363-A1 THIADIAZOLE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, INCLUDING SAME CUREVERSE INCORPORATED (KR) 2025-06-19 US disclosed
EP-4495106-A1 THIADIAZOLE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, INCLUDING SAME Daegu-Gyeongbuk Medical Innovation Foundation (KR) 2025-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250197363-A1 THIADIAZOLE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, INCLUDING SAME PPARD, PPARG, PPARA PPARD 1/4885PPARA 3/4885QPCT 2400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.