SCHEMBL31333801

SCHEMBL31333801

CCOC(=O)C(C)(C)Oc1ccc(SCc2nnc(-c3ccc(F)c(Cl)c3)s2)cc1C

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 18/20 0.49
PPARA Q07869 15/20 0.49
PPARG P37231 6/20 0.49
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
QPCT Q16769 1/20 0.38
QPCTL Q9NXS2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333820 0.92 PPARD (0.49) PPARDPPARAPPARGMEN1ALDH1A1
SCHEMBL30579914 0.91 PPARD (0.60) PPARDPPARAPPARG
SCHEMBL25397535 0.91 PPARD (0.60) PPARDPPARAPPARG
SCHEMBL31408955 0.89 PPARD (0.47) PPARDPPARAPPARG
SCHEMBL30579921 0.88 PPARD (0.60) PPARDPPARAPPARGMEN1ALDH1A1
SCHEMBL25394813 0.88 PPARD (0.60) PPARDPPARAPPARGMEN1ALDH1A1
SCHEMBL31333831 0.87 PPARD (0.48) PPARDPPARAPPARGHPGDQPCT
SCHEMBL31333845 0.85 PPARD (0.58) PPARDPPARAPPARG
SCHEMBL31333921 0.85 PPARD (0.58) PPARDPPARAPPARG
SCHEMBL31333868 0.84 PPARD (0.39) PPARDPPARAPPARGMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197363-A1 THIADIAZOLE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, INCLUDING SAME CUREVERSE INCORPORATED (KR) 2025-06-19 US disclosed
EP-4495106-A1 THIADIAZOLE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, INCLUDING SAME Daegu-Gyeongbuk Medical Innovation Foundation (KR) 2025-01-22 EP disclosed
CN-119212981-A Thiadiazole compound and pharmaceutical composition for preventing or treating inflammatory diseases comprising the same 财团法人 大邱庆北尖端医疗产业振兴财团 2024-12-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250197363-A1 THIADIAZOLE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, INCLUDING SAME PPARD, PPARG, PPARA PPARD 1/4885PPARA 3/4885PPARG 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.