SCHEMBL31333960

SCHEMBL31333960

Cn1c(=O)n(C2CCC(=O)NC2=O)c2ccc(C3CCN(CCN4CCC(C(=O)O)CC4)CC3)cc21

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 3/20 0.54
▸ CRBN Q96SW2 3/20 0.54
▸ IKZF2 Q9UKS7 14/20 0.42
▸ IKZF1 Q13422 1/20 0.38
▸ DRD2 P14416 1/20 0.38
▸ SLC6A4 P31645 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25036615 0.91 DDB1 (0.58) DDB1CRBNIKZF2
SCHEMBL25036590 0.91 DDB1 (0.58) DDB1CRBNIKZF2
SCHEMBL30273456 0.91 DDB1 (0.58) DDB1CRBNIKZF2
SCHEMBL22526963 0.90 DDB1 (0.55) DDB1CRBNIKZF2IKZF1DRD2
SCHEMBL23540460 0.90 DDB1 (0.56) DDB1CRBNIKZF2IKZF1
SCHEMBL23540165 0.90 DDB1 (0.56) DDB1CRBNIKZF2IKZF1
SCHEMBL23540806 0.90 DDB1 (0.56) DDB1CRBNIKZF2IKZF1
Hydrochloric Acid SCHEMBL30258255 0.89 DDB1 (0.56) DDB1CRBNIKZF2IKZF1
SCHEMBL30289187 0.89 DDB1 (0.57) DDB1CRBNIKZF2IKZF1DRD2
SCHEMBL22526962 0.88 DDB1 (0.53) DDB1CRBNIKZF2IKZF1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
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