SCHEMBL31334099

SCHEMBL31334099

CNC(=O)[C@H]1CC[C@H](Nc2ncc(Cl)c(-c3cc(C4CC4)[nH]n3)n2)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 2/20 0.41
CDK2 P24941 10/20 0.41
MAPK8 P45983 9/20 0.41
MAPK9 P45984 9/20 0.41
JUN P05412 8/20 0.41
MAPK10 P53779 7/20 0.41
PDGFRB P09619 1/20 0.40
PDGFRA P16234 1/20 0.40
CDK9 P50750 2/20 0.39
CDK7 P50613 1/20 0.39
NTRK1 P04629 1/20 0.39
IGF1R P08069 2/20 0.38
CCNE1 P24864 2/20 0.38
CCNB2 O95067 1/20 0.38
CCNE2 O96020 1/20 0.38
CDK1 P06493 1/20 0.38
CCNB1 P14635 1/20 0.38
CDK5 Q00535 1/20 0.38
CDK5R1 Q15078 1/20 0.38
CCNB3 Q8WWL7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334278 1.00 CCNT1 (0.41) CCNT1CDK2MAPK8MAPK9JUN
SCHEMBL31334720 0.93 NTRK1 (0.40) CCNT1CDK2MAPK8MAPK9JUN
SCHEMBL31334743 0.93 NTRK1 (0.40) CCNT1CDK2MAPK8MAPK9JUN
SCHEMBL31334955 0.86 MAPK8 (0.49) CCNT1CDK2MAPK8MAPK9JUN
SCHEMBL31334746 0.83 MAPK3 (0.49) CDK2MAPK8MAPK9JUNMAPK10
SCHEMBL31334757 0.78 MAPK3 (0.51) CCNT1CDK2MAPK8MAPK9JUN
SCHEMBL31334363 0.74 CCNT1 (0.49) CCNT1CDK2MAPK8MAPK9JUN
SCHEMBL31335021 0.74 CCNT1 (0.49) CCNT1CDK2MAPK8MAPK9JUN
SCHEMBL31333678 0.71 HCAR2 (0.43) IGF1R
SCHEMBL31334476 0.71 HCAR2 (0.43) IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed