SCHEMBL31334196

SCHEMBL31334196

O=C1CCC(Nc2ccc(N3CCC(N4CC5(CC(C(=O)O)C5)C4)CC3)c(F)c2)C(=O)N1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 19/20 0.43
CRBN Q96SW2 19/20 0.43
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333516 0.89 DDB1 (0.47) DDB1CRBNMEN1MAPTKMT2A
SCHEMBL31333636 0.89 CRBN (0.46) DDB1CRBN
SCHEMBL31334345 0.87 DDB1 (0.48) DDB1CRBN
SCHEMBL25175457 0.87 DDB1 (0.52) DDB1CRBNMEN1MAPTKMT2A
Hydrochloric Acid SCHEMBL27178791 0.86 DDB1 (0.51) DDB1CRBNMEN1MAPTKMT2A
SCHEMBL31333699 0.86 DDB1 (0.47) DDB1CRBNMEN1MAPTKMT2A
SCHEMBL31334304 0.86 DDB1 (0.47) DDB1CRBNMEN1MAPTKMT2A
SCHEMBL31334212 0.83 DDB1 (0.57) DDB1CRBN
SCHEMBL31334059 0.82 DDB1 (0.45) DDB1CRBNMEN1MAPTKMT2A
SCHEMBL31333809 0.82 DDB1 (0.47) DDB1CRBNMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed