Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 3/20 | 0.35 |
| ▸ | CDK4 | P11802 | 3/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335033 | 1.00 | BTK (0.38) | BTKMEN1MAPTKMT2AJAK2 | |
| SCHEMBL31333903 | 0.95 | JAK2 (0.39) | BTKMEN1MAPTKMT2AJAK2 | |
| SCHEMBL31334706 | 0.94 | MEN1 (0.37) | MEN1MAPTKMT2ACCNT1CCNA2 | |
| SCHEMBL31333687 | 0.94 | MEN1 (0.37) | MEN1MAPTKMT2ACCNT1CCNA2 | |
| SCHEMBL31333256 | 0.93 | BTK (0.35) | BTKMEN1MAPTKMT2AJAK2 | |
| SCHEMBL31334643 | 0.93 | BTK (0.35) | BTKMEN1MAPTKMT2AJAK2 | |
| SCHEMBL31333972 | 0.93 | JAK2 (0.37) | BTKJAK2JAK1JAK3CCNT1 | |
| SCHEMBL31334658 | 0.93 | JAK2 (0.37) | BTKJAK2JAK1JAK3CCNT1 | |
| SCHEMBL31334478 | 0.91 | MEN1 (0.39) | BTKMEN1MAPTKMT2ACCNT1 | |
| SCHEMBL31335019 | 0.91 | MEN1 (0.39) | BTKMEN1MAPTKMT2ACCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |