1,3-Propanediol

1,3-Propanediol

SCHEMBL3133442

[2H]C([2H])(O)C([2H])([2H])C([2H])([2H])O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL2537863 0.89
1,3-Propanediol SCHEMBL32660964 0.80
Ethylene Glycol SCHEMBL2307225 0.76
Butyl Alcohol SCHEMBL19899953 0.74
SCHEMBL1330915 0.74
1,4-Butanediol SCHEMBL14477517 0.74
Butyl Alcohol SCHEMBL19899826 0.74
3-Chloropropanol SCHEMBL13750816 0.74
1,4-Butanediol SCHEMBL31172891 0.74
SCHEMBL14477544 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617768-B2 Radiolabeled cannabinoid receptor 2 ligand HOFFMANN-LA ROCHE INC. (US) 2026-05-05 US disclosed
EP-3813888-B1 RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND HOFFMANN LA ROCHE (CH) 2025-11-26 EP disclosed
US-20250179026-A1 Deuterium-Enriched 3,5-Dimethylpyrazolyl-3-propoxy-4-fluorobenzoic Acids for Treatment of Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) and Polyneuropathy (ATTR-PN), and Related Diseases DHANOA DALJIT SINGH (US) 2025-06-05 US disclosed
EP-3814337-B1 PYRIDINE AND PYRAZINE DERIVATIVES AS PREFERENTIAL CANNABINOID 2 AGONISTS HOFFMANN LA ROCHE (CH) 2025-05-14 EP disclosed
WO-2024218296-A1 COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF LEUCINE-RICH REPEAT KINASE 2 (LRRK2) INHIBITORS H. LUNDBECK A/S (DK) 2024-10-24 WO disclosed
US-20240308974-A1 RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND HOFFMANN LA ROCHE (US) 2024-09-19 US disclosed
EP-3577118-B1 COMPOUNDS FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION GILEAD SCIENCES INC (US) 2024-09-04 EP disclosed
EP-4422750-A1 LRRK2 INHIBITORS H. Lundbeck A/S (DK) 2024-09-04 EP disclosed
CN-118251397-A LRRK2 inhibitors H.隆德贝克有限公司 2024-06-25 CN disclosed
US-11999710-B2 Radiolabeled cannabinoid receptor 2 ligand HOFFMANN-LA ROCHE INC. (US) 2024-06-04 US disclosed
EP-2897948-B1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS HEPTARES THERAPEUTICS LTD (GB) 2016-08-31 EP disclosed
US-20160128996-A1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS NXERA PHARMA UK LIMITED (GB) 2016-05-12 US disclosed
US-20160128996-A1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS NXERA PHARMA UK LIMITED (GB) 2016-05-12 US disclosed
US-9266857-B2 Bicyclic AZA compounds as muscarinic M1 receptor agonists HEPTARES THERAPEUTICS LIMITED (GB) 2016-02-23 US disclosed
US-9266857-B2 Bicyclic AZA compounds as muscarinic M1 receptor agonists HEPTARES THERAPEUTICS LIMITED (GB) 2016-02-23 US disclosed
US-20150232443-A1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS NXERA PHARMA UK LIMITED (GB) 2015-08-20 US disclosed
US-20150232443-A1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS NXERA PHARMA UK LIMITED (GB) 2015-08-20 US disclosed
EP-2897948-A1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS Heptares Therapeutics Limited (GB) 2015-07-29 EP disclosed
WO-2014045031-A1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS HEPTARES THERAPEUTICS LIMITED (GB) 2014-03-27 WO disclosed
US-20100076010-A1 ALPHA 1A-ADRENOCEPTOR ANTAGONISTS CONCERT PHARMACEUTICALS, INC. 2010-03-25 US disclosed