Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334949 | 1.00 | IRAK1 (0.46) | IRAK1MAPK1TBK1NR4A2DHODH | |
| SCHEMBL31333579 | 0.91 | PDGFRB (0.41) | IRAK1MAPK1NR4A2DHODHCDK1 | |
| SCHEMBL31334424 | 0.85 | IRAK1 (0.45) | IRAK1MAPK1TBK1CCNT1CDK1 | |
| SCHEMBL31333519 | 0.85 | IRAK1 (0.45) | IRAK1MAPK1TBK1CCNT1CDK1 | |
| SCHEMBL31334177 | 0.83 | MAPK8 (0.44) | IRAK1MAPK1CCNT1CDK1CCNB1 | |
| SCHEMBL31334490 | 0.83 | MAPK1 (0.40) | IRAK1MAPK1CCNT1CDK1CCNB1 | |
| SCHEMBL31333798 | 0.83 | MAPK1 (0.40) | IRAK1MAPK1CCNT1CDK1CCNB1 | |
| SCHEMBL31333629 | 0.82 | CDK2 (0.47) | IRAK1MAPK1CDK1CCNB1CCNE1 | |
| SCHEMBL31334535 | 0.82 | IRAK1 (0.45) | IRAK1MAPK1CCNT1CDK1CCNB1 | |
| SCHEMBL31334123 | 0.81 | MAPK3 (0.47) | IRAK1MAPK1CCNT1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |