Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 3/20 | 0.36 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CCND1 | P24385 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333753 | 0.91 | MAPK1 (0.46) | MAPK1MAP4K1CDK1CDK4CCND1 | |
| SCHEMBL31334239 | 0.91 | MAPK1 (0.46) | MAPK1MAP4K1CDK1CDK4CCND1 | |
| SCHEMBL31334585 | 0.89 | MAP4K1 (0.42) | MAPK1MAP4K1CDK1CDK4CCND1 | |
| SCHEMBL31333937 | 0.88 | CKS1B (0.42) | MAPK1CKS1BSKP1SKP2MERTK | |
| SCHEMBL31334133 | 0.88 | MAPK1 (0.49) | MAPK1CKS1BSKP1SKP2MERTK | |
| SCHEMBL31333533 | 0.88 | MAPK1 (0.43) | MAPK1CKS1BSKP1SKP2MERTK | |
| SCHEMBL31333253 | 0.86 | MAPK1 (0.49) | MAPK1CKS1BSKP1SKP2MAP4K1 | |
| SCHEMBL31334437 | 0.86 | MAPK1 (0.43) | MAPK1MAP4K1RAF1BRAFMAPK14 | |
| SCHEMBL31334500 | 0.85 | MAP4K1 (0.41) | MAPK1MAP4K1PIK3CACDK1CDK4 | |
| SCHEMBL31334841 | 0.84 | CDK2 (0.42) | MAPK1MAP4K1CDK1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |