Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | PIM1 | P11309 | 4/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 4/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334197 | 1.00 | ADORA1 (0.52) | ADORA1PIM1AXLTYRO3MERTK | |
| SCHEMBL31333867 | 1.00 | ADORA1 (0.52) | ADORA1PIM1AXLTYRO3MERTK | |
| SCHEMBL31334729 | 0.86 | CCNT1 (0.53) | ADORA1AXLTYRO3MERTKADORA2A | |
| SCHEMBL31334905 | 0.86 | CCNT1 (0.53) | ADORA1AXLTYRO3MERTKADORA2A | |
| SCHEMBL31334093 | 0.86 | CCNT1 (0.53) | ADORA1AXLTYRO3MERTKADORA2A | |
| SCHEMBL31334355 | 0.85 | MAPK3 (0.52) | ADORA1ADORA2ACDK7CDK9CCNT1 | |
| SCHEMBL31334779 | 0.85 | MAPK3 (0.56) | ADORA1ADORA2ACDK7CDK9CCNT1 | |
| SCHEMBL31333846 | 0.85 | MAPK3 (0.56) | ADORA1ADORA2ACDK7CDK9CCNT1 | |
| SCHEMBL31334595 | 0.85 | MAPK3 (0.56) | ADORA1ADORA2ACDK7CDK9CCNT1 | |
| SCHEMBL18069763 | 0.85 | PIM1 (0.49) | ADORA1PIM1CDK7CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |