Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 4/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CCNK | O75909 | 2/20 | 0.38 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CCNH | P51946 | 2/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334973 | 0.88 | MAPK8 (0.41) | MAPK8MAPK14MAPK1MAPK10MAPK9 | |
| SCHEMBL31333694 | 0.88 | MAPK14 (0.44) | MAPK8MAPK14MAPK1MAPK9CCNE1 | |
| SCHEMBL31333452 | 0.88 | MAPK8 (0.50) | MAPK8MAPK14MAPK1MAPK10MAPK9 | |
| SCHEMBL31335041 | 0.88 | CDK2 (0.39) | MAPK1ADORA1ADORA2AADORA2BCCNE1 | |
| SCHEMBL31335133 | 0.83 | CCNE1 (0.43) | MAPK8MAPK14MAPK1MAPK10MAPK9 | |
| SCHEMBL31334517 | 0.83 | CSNK2A2 (0.49) | MAPK8MAPK14MAPK10MAPK9MCHR1 | |
| SCHEMBL31334624 | 0.82 | CCNK (0.41) | MAPK8MAPK1CCNE1CDK2CCNT1 | |
| SCHEMBL31333835 | 0.81 | MCHR1 (0.44) | MAPK8MAPK14MAPK1MAPK10MAPK9 | |
| SCHEMBL31334783 | 0.81 | MAPK8 (0.45) | MAPK8MAPK14MAPK1MAPK10MAPK9 | |
| SCHEMBL31334177 | 0.80 | MAPK8 (0.44) | MAPK8MAPK14MAPK1MAPK10MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |